Jump to the main content block




姓名: 蔡振寧
職稱: 助理教授
學歷: 博士: 國立台灣大學理學院生化科學研究所  
           碩士: 國立台灣大學醫學院生化學研究所 
           學士: 台北醫學院醫事技術系
聯絡電話: 04-24730022 #11720、11727
專長:Wnt 訊息傳遞在斑馬魚胚胎發育上之角色、胚胎發育學
教授科目:生物化學、 分子遺傳學、胚胎發育學、血液學、血庫學


  1. Lee HC, Lin YZ, Lai YT, Huang WJ, Hu JR, Tsai JN, Tsai HJ*. Glycogen Synthase Kinase 3 beta in somites plays a role during the angiogenesis of zebrafish embryos.FEBS J. 2014 Jul 23. doi: 10.1111/febs.12942.
  2. Lo KC, Sun CY, Ding KJ, Tsai JN, Chang KP, Wen YE, Chang WL, Chang SC, Chang MF, Wang YH, Chen YH*. Nephrotoxicity assessments of benzo(a)pyrene during zebrafish embryogenesis. Res Chem Intermediat. 2014, 40 (6): 2177-2185.
  3. Chang WN, Lee GH, Kao TT, Lin CY, Hsiao TH, Tsai JN, Chen BH, Chen YH, Wu HR, Tsai HJ, Fu TF*. Knocking down 10-formyltetrahydrofolate dehydrogenase increased oxidative stress and impeded zebrafish embryogenesis by obstructing morphogenetic movement Biochim Biophys Acta. 2014,1840(7):2340-50.
  4. Chen MH, Hsu LC, Wu JL, Yeh CW, Tsai JN, Hseu YC, Hsu LS*. Exposure to benzidine caused apoptosis and malformation of telencephalon region in zebrafish. Environ Toxicol. 2013 Jun 13. doi: 10.1002/tox.21873.
  5. Yeh CH, Liao YF, Chang CY, Tsai JN, Wang YH, Cheng CC, Wen CC, Chen YH*. Caffeine treatment disturbs the angiogenesis of zebrafish larvae. Drug Chem. Toxicol. 2012, 35(4): 361-365.
  6. Liao YF, Chiou MC, Tsai JN, Wen CC, Wang YH, Cheng CC*,Chen YH*. Resveratrol treatment attenuates the wound-Induced inflammation in zebrafish larvae through the suppression of myeloperoxidase expression.J. Food Drug Analysis. 2011, 19(2): 167-173.
  7. Hsu LS *, Liang CJ, Tseng CY, Yeh CW, Tsai JN. Zebrafish cyclin-dependent protein kinase –like 1 (zcdkl1): identification and functional characterization.Int. J. Mol. Sci. 2011, 12(6) : 3606-3617.
  8. Wang YH, Wen CC, Yang ZS, Cheng CC, Tsai JN, Ku CC, Wu HJ, Chen YH*. Development of a whole- organism model to screen new compounds for sun protection. Mar Biotechnol (NY). 2009, 1(3):419-29.
  9. Kao TT, Wang KC, Chang WN, Lin CY, Chen BH, Wu HL, Shi GY, Tsai JN, Fu TF*. Characterization and comparative studies of zebrafish and human recombinant dihydrofolate reductases – inhibition by folic acid and polyphenols. Drug Metab Dispos 2008, 36(3):508-16. (SCI)
  10. Lee HC, Tsai JN, Liao PY, Tsai WY, Lin KY, Chung CC, Sun CK, Chang WC and Tsai HJ*. Glycogen synthase kinase 3α and 3β have distinct functions during cardiogenesis of zebrafish embryo. BMC Dev Biol 2007, 3; 7:93. (SCI)
  11. Chang WN, Tsai JN, Chen BH,Huang Hs and Fu TH*. Serine hydroxymethyltransferase isoforms are differentially inhibited by leucovorin – characterization and comparison of the recombinant zebrafish serine hydroxymethyltransferases. Drug Metab Dispos. 2007, 35(11):2127-37. (SCI)
  12. Chang WN, Tsai JN, Chen BC and Fu TF*. Cloning, expression, purification and characterization of zebrafish cytosolic serine hydroxymethyltransferase. Protein Expr Purif 2006, 46: 212-20. (SCI)
  13. Chen YJ*, Hsu KW, Tsai JN, Hung CH, Kuo TC and Chen YL. Involvement of protein kinase C in the inhibition of lipopolysaccharide-induced nitric oxide production by thapsigargin in RAW 264.7 macrophages Int JBiochem Cell Biol 2005, 37: 2574-85. (SCI)
  14. Tsai JN, Lee CH, Jeng H, Chi WK and Chang WC*, Differential expression of glycogen synthase kinase 3 genes during zebrafish embryogenesis . Mech Dev 2000, 91: 387-391. (SCI)

1.     Weng CY, Chen CK, Chang CF, Tsai JN. N-glycosylation is required for efficient secretion of R-spondin 1. (2014) The 29th Joint Annual Conference of Biomedical Sciences. Taipei, R.O.C. Abs#P158.
2.     Ye MD, Chang CF, Tsai JN Characterization of Zebrafish Zinc Ring Finger 3 Gene. (2014) The 29th Joint Annual Conference of Biomedical Sciences. Taipei, R.O.C. Abs#P159.
3.     Chang CF, Chen YH, Lin H, Fu TF, Tsai JN. Rspo3 is required for arterial differentiation during zebrafish embryogenesis. (2011) 2011 Taiwan zebrafish symposium. Academic Sinica, Taipei, R.O.C. Abs#P40.
4.     Chang CF, Lin H, Tsai JN. Glycogen synthase kinase 3α is required for epiboly movement. (2011) 7th European Zebrafish Meeting, Edinburg, UK. Abs#P1-142.
5.     Chang CF, Lin H, Tsai JN. rspo3 is required for the angiogensis and the artery differentiation during zebrafish embryogenesis (2010) 43rd Annual Meeting for the Japanese Society of Developmental Biologists. Kyoto, Japan. Abs#P168.
6.     Chang CF, Lin H, Tsai JN. Rspo3 is essential for the establishment of cardiac asymmetry during zebrafish embryogenesis (2010) The 25th Joint Annual Conference of Biomedical Sciences. Taipei, R.O.C. Abs#P760.
7.     Chang CF, Liu CK, Yang YT, Chen YH, Lin H, Hsieh DJY, Tsai JN. Depletion of rspo3 suppresses Wnt/β-catenin signaling during zebrafish embryogenesis (2009) The 24th Joint Annual Conference of Biomedical Sciences. Taipei, R.O.C. Abs#P570.
8.     Yang YT, Chang WC, Cheng CH, Tsai JN, Chen CH, Chang WC. Protein expression profiles during zebrafish oocyte-to-zygote transition (2008) The 23th Joint Annual Conference of Biomedical Sciences. Taipei, R.O.C. Abs#P
9.     Tsai JN, Lee ZY, Cheng CH, Chou JL. Cloning and expression of zebrafish translin-associated factor X (TRAX) (2007) The 22th Joint Annual Conference of Biomedical Sciences. Taipei, R.O.C. Abs#P554.
10. Chang WN, Tsai JN, Chen BC, Fu TF. Cloning, expression, purification, and characterization of zebrafish serinehydroxymethyltransferase (2006) The 21th Joint Annual Conference of Biomedical Sciences. Taipei, R.O.C. Abs#P628.
11.Tsai JN, Chen CH, Chen YJ, Chen YL, Chen JY and Chang WC. Combinatorial Wnts regulate the expression of axin2 during zebrafish neurogenesis. (2005) The 20th Joint Annual Conference of Biomedical Sciences. Taipei, R.O.C. Abs#P140.