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  5. 李瑤玲老師

李瑤玲老師

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姓名：李瑤玲
職稱：副教授
學歷：碩士：中山醫學院生化所
          學士：中山醫學院醫事技術學系
聯絡電話：04-24730022#12417
E-Mail：yllee@csmu.edu.tw
專長：肺炎與肺癌相關之免疫學研究
教授科目：血清免疫學、血清免疫學實驗、免疫學、臨床鏡檢學、臨床鏡檢學實驗、臨床生理學、自體免疫學概論

 

期刊論文------期刊論文

 

  1. Yao-Ling Lee, Wu-Hsien Kuo, Chiao-Wen Lin, Wei Chen, Wei-Erh Cheng, Shuo-Chueh Chen, Chuen-Ming Shih*. Association of genetic polymorphisms of CXCL12/SDF1 gene and its receptor, CXCR4, to the susceptibility and prognosis of non-small cell lung cancer. Lung Cancer. 2011 Aug;73(2):147-52. (SCI, IF=3.356) 
  2.  Chuen-Ming Shih, Wu-Hsien Kuo, Chiao-Wen Lin, Wei Chen, Wei-Erh Cheng, Shuo-Chueh Chen, Yao-Ling Lee*. Association of polymorphisms in the genes of urokinase plasminogen activation system with susceptibility to and severity of non-small cell lung cancer. Clinica Chimica Acta. 2011 Jan 14;412(1-2):194-8. (SCI, IF=2.535)
  3.  Yu-Chiao Yi, Shih-Chi Wang, Chun-Chin Chao, Chia-Ling Su, Yao-Ling Lee, and Ling-Yun Chen*; Evaluation of Serum Autoantibody Levels in the Diagnosis of Ovarian Endometrioma. Journal of Clinical Laboratory Analysis. 2010;24(5): 357-62. (SCI, IF=0.855)
  4. Yao-Ling Lee1, Wei Chen1, Ling-Yun Chen, Chia-Hung Chen, Yu-Chao Lin, Shinn-Jye Liang and Chuen-Ming Shih*; Systemic and bronchoalveolar cytokines as predictors of in-hospital mortality in severe community-acquired pneumonia.Journal of Critical Care. 2010 Mar;25(1):176.e7-13. (SCI, IF=2.077) 1These authors contributed equally to this work.
  5. Ming-Cheng Chan, Jeng-Yuan Hsu, Hsiu-Hwa Liu, Yao-Ling Lee, Su-Chen Pong, Li-Yin Chang, Benjamin Ing-Tiau Kuo, Chieh-Liang Wu*; Effects of prone position on inflammatory markers in patients with ARDS due to community-acquired pneumonia. J Formos Med Assoc. 2007 Sep;106(9):708-16. (SCI, IF=0.661)   
  6. Yih-Shou Hsieh1, Yao-Ling Lee1, Shun-Fa Yang, Jia-Sin Yang, Wei Chen, Shuo-Chueh Chen, Chuen-Ming Shih*; Association of EcoRI Polymorphism of the Metastasis-Suppressor Gene NME1 with Susceptibility to and Severity of Non-Small Cell Lung Cancer. Lung Cancer. 2007;58(2):191-195,. (SCI, IF=3.140) 1These authors contributed equally to this work.
  7.  Wang L, Chang YH, Lee YL, Shih CM, Hsu YT, Shen GH, Haung ML, Shiau MY*; Autoantibodies against tumor suppressor gene p53 in pleural effusions of patients with non-malignancy. Annals of Clinical Biochemistry. 2007 Jan;44 (Pt 1):57-62.  (SCI, IF=1.917)
  8. Xu F, Yang Z, Wang L, Lee YL, Yang CC, Xiao SY, Xiao H, Wen L; Morphological Characterization of Hantavirus HV114 by Electron Microscopy. Intervirology. 2007 Jan 26;50(3):166-172. (SCI, IF=1.106)
  9. Yao-Ling Lee, Wei Chen, Wen-Kai Tsai, Jen-Chih Lee, Hui-Ling Chiou, Chuen-Ming Shih*, Yi-Ching Wang; Polymorphisms of p53 and p21 genes in Chronic Obstructive Pulmonary Disease. Translational Research, Journal of Laboratory and Clinical Medicine. 2006;147(5):228-233. (SCI, IF=2.062)
  10. Chuen-Ming Shih*, Yao-Ling Lee, Hui-Ling Chiou, Wei Chen, Gee-Chen Chang, Ming-Chih Chou, Long-Yau Lin; Association of TNF-α Polymorphism with Susceptibility to and Severity of Non-Small Cell Lung Cancer. Lung Cancer. 2006;52(1):15-20. (SCI, IF=3.140)
  11.  Wu CL, Chan MC, Chang GC, Lee YL, Chin CS, Chang KM, Hsu JY*. Etiology and Cytokine Expression in Patients Requiring Mechanical Ventilation Due to Severe Community-acquired Pneumonia. J Formos Med Assoc. 2006;105(1):49-55. (SCI IF=0.661)
  12. Chuen-Ming Shih1*, Yao-Ling Lee1, Hui-Ling Chiou, Wei-Fang Hsu, Wei-Erh Chen, Ming-Chih Chou, Long-Yau Lin. The involvement of genetic polymorphism of IL-10 promoter in non-small cell lung cancer. Lung Cancer 50(3):291-297, 2005. (SCI, IF=3.140) 1These authors contributed equally to this work.
  13. Fang-Ling Xu, Yao-Ling Lee, Wei-Yu Tsai, Shyh-Jye Lin, Zhan-Qiu Yang, Chi-Chiang Yang*, Han-Yan Liu, Li Cheng, Hong Xiao, Li Wen. Effect of cordycepin on Hantaan virus 76-118 infection of primary human embryonic pulmonary fibroblasts--characterization of apoptotic effects. Acta Virologica 49(3):183-93, 2005. (SCI, IF=0.746)
  15. Yao-Ling Lee, Chuen-Ming Shih, Hui-Ling Chiou, Ming-Yuh Shiau, Gee-Chen Chang, and Yih-Hsin Chang*. Alteration of autoantibodies against p53 in Taiwanese lung cancer patients undergoing chemotherapy. Clinica Chimica Acta 349:87-96, 2004. (SCI, IF=2.960)
  16. Chang YH, Wu CH, Lee YL, Huang PH, Kao YL, and Shiau MY*. Evaluation of NMP22 as a Clinical Diagnostic Marker for Bladder Cancer. Urology.64:687-692, 2004. (SCI, IF=2.130)
  17. Yao-Ling Lee, Hui-Ling Chiou, Sern-Nan Hu, and Lina Wang*. Analysis of RHD Genes in Taiwanese RhD-Negative Donors by the Multiplex PCR Method. Journal of Clinical Laboratory Analysis 17:80–84, 2003. (SCI, IF=1.117)
  18. Chieh-Liang Wu, MD*; Yao-Ling Lee, MS; Kai-Ming Chang, MD; Gee-Chen Chang, MD; Shiang-Liang King, BS; Chi-Der Chiang, MD; and Michael S. Niederman, MD. Bronchoalveolar interleukin-1b: A marker of bacterial burden in mechanically ventilated patients with community-acquired pneumonia Critical Care Medicine 31:812–817, 2003. (SCI, IF=6.599)
  19. Shiau MY, Kuo TM, Tsay GJ, Chiou HL, Lee YL, and Chang YH*. Absence of anti-p53 antibodies in Chinese patients with rheumatoid arthritis and systemic lupus erythematosus: comment on the concise communication by Kovacs et al. Arthritis & Rheumatism 46:276, 2002. (SCI, IF=7.421)
  20. Yao-Ling Lee, Sern-Nan Hu, Hui-Ling Chiou and Lina Wang*. Phenotyping of Rh Blood Group in Taichung Area. J Biomed Lab Sci 13:84-88, 2001.
  21. Ming-Yuh Shiau, Hui-Ling Chiou, Yao-Ling Lee, Tzer-Min Kuo, and Yih-Hsin Chang*. Establishment of a consistent L929 bioassay system for TNF-alpha quantitation to evalute the effect of lipopolysaccharide, phytomitogens and cytodifferentiation agents on cytotoxicity of TNF-alpha secreted by adherent human mononuclear cells. Mediators of inflammation 10:199-208, 2001. (SCI, IF=0.953)
  22. D-B LIN*, H-M Wang, Y-L Lee, U-P Ling, and C-J Chen. Immune Status in preschool children born after mass hepatitis B vaccination program in central . Vaccine 16(17):1683-1687, 1998. (SCI, IF=2.822)
  23.  Rong-Tai Tsai, Meilin Wang, Wei-Chih Ou, Yao-Ling Lee, Shuan-Yow Li, Chiung Yau Fung, Yih-Leh Hung, Tsair-Yuh Tzeng, Yueh Chen, and Deching Chang*. Incidence of JC Viruria is Higher Than That of BK Viruria in . Journal of Medical Virology 52:253-257, 1997. (SCI, IF=2.520)

     

 

期刊論文------研討會論文

 

  1.  Y.-L. Lee, C.-J. Liu, C.-C. Chu , W. Chen, and C.-M. Shih. Impact of ’s Integrated Prospective Payment on Prolonged Mechanical Ventilation: a Six-Year Nationwide Study. American Thoracic Society 2011 International Conference. Denver, . [Publication Page:A5058]
  2. Yao-Ling Lee, Wei Chen, Wer-Erh Cheng, Shuo-Chueh Chen, and Chuen-Ming Shih. Contribution of genetic polymorphism of stromal cell-derived factor-1 (SDF-1) and its receptor, CXCR4, to the susceptibility and severity of non-small cell lung cancer. 20th European Respiratory Society Annual Congress, Barcelona, . European Respiratory Journal 2010 Sep;36 (S54):[P3240]
  3.  Y.-L. Lee, W. Chen, W.-E. Cheng, S.-C. Chen, and C.-M. Shih. Measurements of weaning index as a predictor of weaning outcome in long-term ventilator dependent patients in . American Thoracic Society 2010 International Conference. New Orleans, . [Publication Page:A3038]
  4.  Y.-L. Lee, W. Chen, W.-E. Cheng, S.-C. Chen, and C.-M. Shih. Measurements of weaning index as a predictor of weaning outcome in long-term ventilator dependent patients in . ATS 2010 New orleans International Conference
  5. YL Lee, W Chen, SC Chen, WE Cheng, and CM Shih. Association of polymorphisms in the genes of the urokinase plasminogen activation system with susceptibility to and severity of non-small cell lung cancer. 19th European Respiratory Society Annual Congress. Vienna, . E-Communication Session. European Respiratory Journal 2009 Sep;34 (S53):[E284]
  6. Y.L.Lee, S.C.Chen, W.Chen, W.E.Cheng, C.M.Shih. The association of MMP-7 and MMP-13 genetic polymorphisms with susceptibility to non-small cell lung cancer in . 18th European Respiratory Society Annual Congress. Berlin, . Oral Presentation. European Respiratory Journal 2008 Oct;32 (S52):[1335]
  7.  SC Chen, YL Lee, W Chen, WE Cheng and CM Shih. Tissue inhibitors of metalloproteinase-2 C-303T and G-418C genetic polymorphisms are associated with an increased risk of non-small cell lung cancer in . 18th European Respiratory Society Annual Congress. Berlin, . Oral Presentation. European Respiratory Journal 2008 Oct;32 (S52):[1334]
  8. Yao-Ling Lee, Shuo-Cheuh Chen, Wei Chen, Wei-Erh Cheng and Chuen-Ming Shih. Association of Hypoxia Inducible Factor-1α Polymorphisms with Susceptibility to Non-small Cell Lung Cancer. American Thoracic Society 2008 International Conference. Toronto, . [Publication Page:A909]
  9. Y. L. Lee, S. F. Yang, S. C. Chen, W. Chen, C. M. Shih. Association of polymorphism of the human nm23-H1 gene (NME1) with susceptibility to and severity of non-small cell lung cancer. 17th European Respiratory Society Annual Congress. Stockholm-Sweden. Oral presentation. European Respiratory Journal 2007 Sep;30 (S51):[1279]
  10.  Y.L. Lee, L.Y. Chen, W. Chen, S.C. Chen, W.E. Cheng, and C.M. Shih. Autoantibodies against p16 and p90 in Taiwanese lung cancer patients. American Thoracic Society 2007 International Conference. San Francisco, . [Publication Page:A381]
  11.  Yao-Ling Lee, Yi-heng Liu, Chia-hung Chen, Chen-feng Chiu, Chia-Ming Chen, and Chuen-Ming Shih, The clinical significance of serum and bronchoalveoalr lavage inflammatory cytokine in patients with acute respiratory failure due to severe community-acquired pneumonia. 16th European Respiratory Society Annual Congress. Munich, . European Respiratory Journal 2006 Sep;28 (S50):[P2075]
  12.  C. M. Shih, Y. L. Lee, I. H. Lee, W. T. Kao, and Y. C. Wang. Association of -93 GA polymorphism in the hMLH1 gene with susceptibility to and prognosis of non-small cell lung cancer in . 16th European Respiratory Society Annual Congress. Munich, . Oral presentation. European Respiratory Journal 2006 Sep;28 (S50):[951].
  13.  C.-M. Shih, S.-C. Chen, Y.-L. Lee, W. Chen, Y.-H. Yu, W.-H. Hsu. The Role of Pleural Fluid C-Reactive Protein Concentration in Discriminating Uncomplicated Parapneumonic Pleural Effusions from Complicated Parapneumonic Effusion and Empyema. American Thoracic Society 2006 International Conference. San Diego, . [Publication Page:A836]
  14.  Chuen-Ming Shih, Yao-Ling Lee, Hui-Ling Chiou, Wei-Erh Chen, Liang-Wen Hang, and Wu-Huei Hsu. Polymorphism of IL-4, IL-10, and TNF-a gene in ChronicObstructive Pulmonary Disease. (2005) European Respiratory Society AnnualCongress, Copenhagen-Denmark. Eur Respir J 26, Suppl. 49, 442s, 2005.
  15.  Shinn-Jye Liang, Yu-Chao Lin, Yao-Ling Lee, Hui-Ling Chiou, Te-Chun Hsia and Chuen-Ming Shih. Polymorphism in the Interleukin-10 Gene Promoter are Associated with Susceptibility to Non-Small Cell Lung Cancer (NSCLC). (2005) European Respiratory Society Annual Congress, Copenhagen-Denmark. Eur Respir J 26, Suppl. 49, 458s, 2005.
  16.  Shih CM and Lee YL. Role of tumor necrosis factor a-gene polymorphisms (-238 and -308) in non-small cell lung cancer susceptibility and severity. (2005) 11th World Conference on Lung Cancer. 3-6 July 2005, Barcelona, . Lung Cancer 49, Supplement 2, S145. P113. July 2005.
  17. Lee YL, Shih CM, Chiou HL, Shiau MY, Chang GC, Chang YH. Alteration of autoantibodies against p53 in Taiwanese lung cancer patients undergoing chemotherapy. (2004) 7th Dresden Symposium on Autoantibodies, Dresden, . Autoantigens, Autoantibodies, Autoimmunity 4, P. 570. 2004.
  18.  Lee YL, Wang L, Shih CM, Chang YH, Chiou HL, Shen GH, Shiau MY. Autoantibodies against tumor suppressor protein p53 in pleural effusions of patients with tuberculosis pleurisy. (2004) 7th Dresden Symposium on Autoantibodies, Dresden, . Autoantigens, Autoantibodies, Autoimmunity 4, P. 571. 2004.
  19.  Lee YL, Shih CM, Shiau MY, Shen GH, Lin LF, Huang CN, and Chang YH*. Anti-p53 autoantibodies in pleural effusions of patients with non-malignant diseases (2002) The 17th Joint Annual Conference of Biomedical Sciences. Taipei , R.O.C. Abs#O24.
  20.  Wu CY, Shiau MY, Huang CN, Lee YL and Chang YH*. Tumor necrosis factor-alpha gene promoter polymorphism in Taiwanese patients with type 2 diabetes mellitus. (2002) The 17th Joint Annual Conference of Biomedical Sciences. Taipei , R.O.C. Abs#P71.
  21. Kuo TM, Shiau MY, Lee YL, Chiou HL,
    Tsai ST
    , Lin LF, and Chang YH*. Absence of anti-p53 antibody in patients with type 1 diabetes mellitus. (2001) The 16th Joint Annual Conference of Biomedical Sciences. Taipei , R.O.C. Abs#O14.
  22.  Shiau MY, Chiou HL, Lee YL, and Chang YH*. Effect of lipopolysaccharide, phytomitogens and cytodifferentiation agents on the production and activity of TNF-anin human mononuclear cells. (2001) The 16th Joint Annual Conference of Biomedical Sciences. Taipei , R.O.C. Abs#P150.
  23.  Kuo TM, Shiau MY,
    Tsai CT
    , Lee YL, Chiou HL, Lin LF, and Chang YH*. Absence of anti-p53 antibody in Chinese patients with rheumatoid arthritis and systemic lupus erythematosus. (2001) The 16th Joint Annual Conference of Biomedical Sciences. Taipei , R.O.C. Abs#P151.