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李明偉老師

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姓名:李明偉  老師
職稱:教授兼醫學檢驗暨生物技術學系系主任
學歷:學士:中山醫學院醫技系

          碩士:中興大學科技法律研究所

          碩士:陽明大學醫學工程研究所

          博士:陽明大學醫學工程研究所  

聯絡電話: 04-24730022 #12412

E-Mail:d880430@csmu.edu.tw
專長:生醫材料、組織工程、生物感測、醫事檢驗

教授科目:組織工程學(研究所) 、高分子材料(研究所)、儀器分析、病理切片技術、醫技學研究方法、論文寫作、奈米生物技術

個人網頁: http://researcher.nsc.gov.tw/Lee/

  

期刊論文-----期刊論文

 

1.      Kai-Chi Ku, Ming-Wei Lee, Shyh Ming Kuo, Chun-Hsu Yao, Shwu-Jen Chang. Preparation and Evaluation of Collagen I/ Gellan Gum/β-TCP Microspheres as Bone Graft Substitute Materials. IEEE Engineering in Medicine and Biology 2013 (In Press)
2.      Shih-Hsien Chang, Kai-Sung Wang, Ming-Wei Lee. Synthesis and Characterization of Cinnamated Polygalacturonic Acid for Biomedical Application.Chung Shan Medical Journal. 2013 (In Press)
3.      Hsiu-Hui Peng, Pin-Jan Liu, I-Min Chen,. Ming-Wei Lee Covalently crosslinked hyaluronan–polygalacturonic acid polymer as the drug carrier and its application in surgery. Iranian Polymer Journal 2013; 22(6): 429-436.
4.      Hsiu-Hui Peng, Yi-Min Chen, Chen-I Lee, Ming-Wei Lee. Synthesis of a disulfide cross-linked polygalacturonic acid hydrogel for biomedical applications. Journal of Materials Science: Materials in Medicine 2013; 24 (6):1375-1382.
5.      Shwu-Jen Chang, Shyh-Ming Kuo, Jhen-Lin You, Ya-Rong Wu, Shu-Ying Chen, Ming-Wei Lee . Physical and Biological Effects of Gellan Gum on Decreasing Post-Operative Adhesion in a Rat Model. Journal of bioactive and compatible polymers 2013; 28(2): 178-187.
6.      Ming-Wei Lee, Hui-Fang Tsai, Shu-Min Wen, Chia-Hui Huang. Photocrosslinkable gellan gum film as an anti-adhesion barrier. Carbohydrate Polymers 2012: 90(2); 11232-11238.
7.      Shwu Jen Chang, Yi-Ting Huang, Yang Shun-Chun, Shyh-Ming Kuo, Ming-Wei Lee. In vitro properties of Gellan gum sponge as the dental filling to mantain alveolar space. Carbohydrate Polymers 2012;88: 486-489.
8.      Ching Jung Chen, Jen Tsai Liu, Shwu-Jen Chang. Ming-Wei Lee, Jang-Zern Tsai. Development of a portable impedance detection system for monitoring the growth of mouse L929 cells. Journal of the Taiwan Institute of Chemical Engineers 2012; 43 (5): 678-684.
9.      Hsiu-Hui Peng, Jia-Wei Chen, Tzi-Peng Yang, Chung-Fan Kuo,Ying-Jiin Wang, Ming-Wei Lee. Polygalacturonic acid hydrogel using short chain hyaluronate (sHA) as the crosslinker with application to prevention of postoperative adhesion. Journal of bioactive and compatible polymers 2011; 26(6): 552-564.
10.   Kai-Sung Wang, Shih-Hsien Chang, Chi-Yuan Lu, Ming-Wei Lee. Fluorescence Immunohistochemistry of Aedes aegypti (L.) Male Accessory Gland MAG-317 Protein for Monitoring Its Transmission Pathway during Copulation. Chung Shan Medical Journal 2011; 22: 187-193.
11.   Ming-Wei Lee Hui-Ju Chen, Shu-Wei Tsao. Preparation, characterization and biological properties of Gellan gum films with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide crosslinker. Carbohydrate Polymers 2010; 82: 920-926.
12.   MW Lee, CW Lan, YT Lin, TW Liu, SM Kuo. Influences of nano-sized type I collagen molecules on hepatocyte cultures. European Cells and Materials 2010; 20(suppl)154.
13.   Shwu-Jen Chang, Shyh-Ming Kuo, Wei-Ting Liu, Cheng-Chie Greory Niu, Ming-Wei Lee, Chun-Shien Wu. Gellan gum film for effective guided bone regeneration. Journal of Medical and Biological Engineering 2010; 30 (2): 99-103.
14.   Tung Kwang Yi, Ming-Wei Lee Collagen coupled with hyaluronic acid: synthesis and soft tissue filler application. Biomedical Engineering: Applications, Basis and Communications 2010; 22(5)401-407.
15.   Kai-Sung Wang, Shih-Hsien Chang, Chi-Yuan Lu, Chung-Hsin Yeh,. Ming-Wei Lee Monitoring paraquat-induced pulmonary fibrosis in rats with Micro-CT finding and histological examination. Journal of Medical and Biological Engineering 2009; 29 (6):312-319.
16.   Yong G. Chen, Ming Wei Lee, Yi H. Tu, Shih C. Hung, Yng J. Wang. Surface coupling of long-chain hyaluronan to the fibrils of reconstituted type II collagen. Artificial Cells, Blood Substitutes, and Biotechnology 2009; 37(5): 222-226.
17.   Ching-Fang Chang, Ming-Wei Lee, Pei-Yin Kuo, Yng-Jiin Wang, Yi-Hsien Tu and Shih-Chieh Hung.  Three-dimensional collagen fiber remodeling by mesenchymal stem cells requires the integrin-matrix interaction. Journal of Biomedical Materials Research Part A 2007; 80A:466-474.
18.   Ming-Wei Lee, Chia-Lu Hung and Yng-Jiin Wang*.  A new anti-adhesion film synthesized from polygalacturonic acid with ethyl-3-(3-dimethylaminopropyl) carbodiimide crosslinker. Biomaterials 2005; 26:3793-3799.
19.   Kai-Sung Wang, Shih-Hsien Chang, Chi-Yuan Lu, Ming-Wei Lee. Fluorescence Immunohistochemistry of Aedes aegypti (L.) Male Accessory Gland MAG-317 Protein for Monitoring Its Transmission Pathway during Copulation. Chung Shan Medical Journal 2011; 22(2): 187-193.
20.   李明偉,研究用離體組織之管制規範,興大法學第八期,頁157-196201011月。
21.   Kai-Sung Wang, Shiuan-Shinn Lee, Shih-Hsien Chang, Chie-Yuan Lu, Shuan-Zhi Chen,. Ming-Wei Lee Evaluation of Daphnia pulex as an indicator of biological toxicity. Chung Shan Medical Journal 2010; 21(3)241-252.
22.   Shih-Hsien Chang, Chi-Yuan Lu, Shiuan-Shinn Lee, Ming-Wei Lee, Chu-Yie Hwang, Kai-Sung Wang. Used hair dye components (p-phenylenediamine,4-aminophenol) to Daphnia pulex. Chung Shan Medical Journal 2010; 21(3)1-17.
23.   Shih-Hsien Chang, Chi-Yuan Lu, Ming-Wei Lee, Shiuan-Shinn Lee, Ping Shyu, Kai-Sung Wang. Effect of two common plant growth regulators (Gibberellic Acid, Paclobutrazol) on freshwater cladoceran (Daphnia pulex). Chung Shan Medical Journal 2009; 20(2)143-159.
24.   Shih-Hsien Chang, Chi-Yuan Lu, Ming-Wei Lee, Shiuan-Shinn Lee, Chin-Chen Hsu, Kai-Sung Wang. The application of surfactants and pesticides on acute toxicity and phototactic swimming behavior model in aquatic animal (Daphnia pulex). Chung Shan Medical Journal 2009; 20(2)125-142.

 

期刊論文-----研討會論文

 

1.      Chia-Hui Huang , Shu-Min Wen, Cheng Luo, Yi Zhao, Ming-Wei Lee*. Prevention of postsurgical adhesion with gellam gum films. 9th World Biomaterials Congress Chengdu, China, June 1-5, 2012.
2.      Yi-Ting Huang , Shwu-Jen Chang, Shyh-Ming Kuo, Ming-Wei Lee*. Application of impedance biosensor in diagnosis myocardial injury. 9th World Biomaterials Congress Chengdu, China, June 1-5, 2012.
3.      Ya-Rong Wu, Shwu-Jen Chang, Shyh-Ming Kuo, Shu-Ying Chen, Jui-Yin Fang, Ming-Wei Lee*. Gellan gum membrane. 9th World Biomaterials Congress Chengdu, China, June 1-5, 2012.
4.      Jui-Yin Fang, Benjamin Teong, Shyh-Ming Kuo, Ching-Jung Chen, Ming-Wei Lee, Jang-Zern Tsai, Shwu-Jen Chang. Screen-printed collagen substrate for the biosensor application. 9th World Biomaterials Congress Chengdu, China, June 1-5, 2012.
5.      Ching-Shu Yen, Benjamin Teong, Ching-Jung Chen, Jang-Zern Tsai, Ming-Wei Lee, Pei-Leun Kang, Jen-Tsai Liu, Shwu-Jen Chang. The study of gelatin as an electrode substrate for biosensor system. 9th World Biomaterials Congress Chengdu, China, June 1-5, 2012.
6.      K.J.Wang, J.Z.Tsai, J.T.Chen, S.J.Chang, M.W.Lee. Portable bio-impedance detection system development. International conference and exhibition on Biosensors and Bioelectronics. Las Vegas USA, May 14-16, 2012.
7.      M.L. Chang, J.Z.Tsai, J.T. Liu, S.J.Chang, M.W.Lee. Developing an impedance measurement system based on electronic design automation for protein detection. International conference and exhibition on Biosensors and Bioelectronics. Las Vegas USA, May 14-16, 2012.
8.      P.J Chen, J.Z.Tsai, J.T. Liu, C.J. Chen, S.J.Chang, M.W.Lee. Paper electrodes. International conference and exhibition on Biosensors and Bioelectronics. Las Vegas USA, May 14-16, 2012.
9.      S.J.Chang, C.S. Yen, C.J. Chen, J.T. Liu, S.M. Kuo, J.Z.Tsai, M.W.Lee. Preparation and characteristics of screen-printing electrode of chitosan. International conference and exhibition on Biosensors and Bioelectronics. Las Vegas USA, May 14-16, 2012.
10.   Y.J. Lin, J.Z.Tsai, J.T. Liu, C.J. Chen, S.J.Chang, M.W.Lee. Screen-printing electrode design for cell behaviors detection by electrical cell-substrate impedance sensing. International conference and exhibition on Biosensors and Bioelectronics. Las Vegas USA, May 14-16, 2012.
11.   Shwu Jen Chang, Ching-Shu Yen, Benjamin Teong, Shyh Ming Kuo, Ching-Jung Chen, Jen-Tsai Liu, Jang-Zern Tsai, Ming-Wei Lee*, "Evaluation of Gelatin as an electrode substrate for biosensor system", NanoBio-Europe 2011, Ireland.
12.   Yi-Ting Huang , Shyh-Ming Kuo, Shwu-Jen Chang, Ming-Wei Lee* , Dental plug based on Gellan gum:    preparation, characterization and in vitro evaluation. International Conference on Biomaterials Science 2011 (ICBS2011),Tsukuba, Japan, March 15th-18th, 2011
13.   Ming-Wei Lee, Shwu Jen Chang, Yi-Ting Lin, Shyh Ming Kuo, Benjamin Teong, Jen-Tsai Liu, Ching-Jung Chen, Jang-Zern Tsai, Cheng-Wen Lan, "Application of Chitosan film in Biosensor", NanoBio-Europe 2011, Ireland.
14.   Cheng-Wen Lan, Shyh-Ming Kuo, Shwu-Jen Chang, Ming-Wei Lee*, "Dental plug based on Gellan gum: preparation, characterization and in vitro evaluation", NanoBio-Europe 2011, Ireland.
15.   Ming Wei Lee*, Shwu Jen Chang, Shyh Ming Kuo, and Kuan Wei Lee. Preparation of Multi-walled Chitosan/Collagen I Microspheres in Controlled Drug Release. 36th CRS Annual Meeting on January 29, 2009, Danmark.
16.   L.Ming-Wei, T. Yi-Hsien, H. Shih-Chieh, W. Yng-Jiin. Chondrogenesis of human mesenchymal stem cells encapsulated in collagen-HA fibrils. First International Conference on Multifunctional, Hybrid and Nanomaterials 15-19 March 2009, France.
17.   Yong Guei Chen, Ming Wei Lee, Shwu Jen Chang, Yi Hsien Tu, Yng Jiin Wang. Syntheses and Characterizations of HA-collagen II hybrid molecules for biomedical applications. The 8th World Biomaterials Congress. 28 May until 1 June 2008, Netherlands.
18.   Ming-Wei Lee, Yen-Shi Kuo , Shih-Chieh Hung, Chiung-Lin Yang and Yng-Jiin Wang. Fibrin/Hyaluronan gel for the chondrogenesis of human mesenchymal stem cells in vitro: 20th European Conference on Biomaterial, France ,Sep 27-Oct 1 2006
19.   Ming-Wei Lee, Yen-Shi Kuo , Shih-Chieh Hung, Chiung-Lin Yang and Yng-Jiin Wang. Fibrin/Hyaluronan gel for   the chondrogenesis of human mesenchymal stem cells in vitro: 20th European Conference on Biomaterial, France ,Sep 27-Oct 1 2006
20.   Ming-Wei Lee, Yng-Jiin Wang* Postsurgical anti-adhesion films based on polygalacturonate with two different crosslinkers 43rd Microsymposium of P.M.M , Prague, 11-15 July 2004.
21.   Ming-Wei Lee, Chia-Lu Hung and Yng-Jiin Wang. Prevention of postsurgical adhesion with photosensitive polygalacturonic acid films 7th World Biomaterials congress, Australia 17-21 May 2004.
22.   Ming-Wei Lee*, Tzi-Peng Yang, Jia-Wei Chen, Hsiu-Hui Peng. Polygalacturonic acid membrane containing Rosmarinic acid: evaluation of drug release in vitro and prevention of postoperative adhesion in vivo. 2011生物醫學工程研討會。
23.   方睿縈、張栩榮、郭士民、陳靖容、劉仁材、蔡章仁、李明偉、張淑真網印膠原蛋白基材研製之研究 2011生物醫學工程研討會。
24.   黃怡婷、李明偉*,以EDC交聯結冷膠薄膜之製備與生物性質研究,2010生物醫學工程研討會。
25.   黃怡婷、張淑真、郭士民、李明偉*3D 結冷膠海綿體的製備與性質分析以及在牙科上之應用,2010生物醫學工程研討會。
26.   林宜亭、藍正文、郭士民、蔡章仁、李明偉、陳靖容、劉仁材、張淑真,網印幾丁聚醣基材製備之研究,2010生物醫學工程研討會。
27.   鄭美惠、郭士民、李明偉、馬亞尼、藍正文、張淑真,結冷膠微粒製備之研究,2010生物醫學工程研討會
28.   曹書瑋、陳慧如、李明偉* Gellan gum之性質、生物相容性及應用評估,2009生物醫學工程研討會。
29.   劉瑋婷、張淑真、郭士民、李明偉*Gellan gum作為牙周再生阻隔膜之研究,2009生物醫學工程研討會。
30.   陳珈瑋、李明偉、郭仲帆、王盈錦,透明質酸與聚半乳糖醛酸之改質以製備水膠,2009生物醫學工程研討會。
31.   董光義(Hung T Hsiao李明偉(Ming W Lee王盈錦(Yng J Wang. 玻尿酸與膠原蛋白偶合物之合成與應用評估. 2008醫學工程年會
32.   李明偉、王盈錦、王亦嵐、黃玲惠、蕭至君、洪嘉璐、孫光蕙、唐士杰 Production and Medical Applications of Hyaluronic Acid. 2002.中日藥物釋放級生醫材料年會

 

期刊論文-----專利

 

1.      United States Patent 20060069063 Crosslinked polygalacturonic acid used for postsurgical tissue adhesion prevention. Inventors:Wang Yng-Jiin, Lee Ming-Wei , Hung Jia-Lu.
2.      台灣專利(證書I257313)一種用於手術後抗組織沾黏的聚半乳糖醛酸交聯物
3.      一種以Gellan gum為基材之傷口敷料(審查中)