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賴雯玲老師

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姓名：賴雯玲  老師
職稱：副教授
學歷：博士：陽明大學生化暨分子生物研究所
          學士：陽明大學醫事技術學系
聯絡電話： 04-24730022 #12421
E-Mail：wllai@csmu.edu.tw
專長: 微生物學、分子生物學與蛋白質工程

 

期刊論文------期刊論文

 

  1. Hsu, C.S., Lai, W.L., Chang, W.W., Liaw, S.H.,* and Tsai, Y.C.* (2002) Structure-based mutational analysis of the D-aminoacylase from Alcaligenes faecalis DA1. Protein Sci. 11:2545-2550.
  2. Lai, W.L., Chou, L.Y., Ting, C.Y., Kirby, R., Tsai, Y.C., Wang, A.H.J., and Liaw, S.H.* (2004) The functional role of the binuclear metal center in D-aminoacylase. One-metal activation and second-metal attenuation. J. Biol. Chem. 279:13962-7.
  3. Huang C. H., Lai W. L., Lee, M. H., Chen C. J., Tsai, Y. C.* and Liaw, S. H.* (2005) Crystal structure of Acremonium strictum glucooligosaccharide oxidase. A novel flavinylation of 6-S-cysteinyl, 8-N1-histidyl FAD. J. Biol. Chem. 280:38831-38838.(Equal first author) 
  4. Lee, M. H., Lai, W. L., Lin, S. F., Hsu, C. S., Liaw, S. H. and Tsai, Y. C.* (2005) Structural characterization of glucooligosaccharide oxidase from Acremonium strictum. Appl. Environ. Microbiol. 71:8881-8887.(Equal first author) 
  5. Lee, M. H., Lai, W. L., Lin, S. F., Liu, Y., Hsu, Y. H. and Tsai, Y. C.* (2006) Purification and characterization of a novel cellooligosaccharide oxidase from rice pathogen Sarocladium oryzae. Enzyme Microbiol. Tech. 39:85-91.
  6. Chun-Hsiang Huang, Andreas Winkler, Chia-Lin Chen, Wen-Lin Lai, Ying-Chieh Tsai, Peter Macheroux, and Shwu-Huey Liaw. (2008) Functional roles of the 6-S-cysteinyl, 8-N1-histidyl FAD in glucooligosaccharide oxidase from Acremonium strictum. J. Biol. Chem. 7;283(45):30990-6.
  7. Wen-Lin Lai, He-Shing Chuang, Meng-Hwan Lee, Chia-Li Wei, Chin-Fu Lin, Ying-Chieh Tsai. (2012) Inhibition of Herpes Simplex Virus Type 1 by Thymol-Related Monoterpenoids. Planta medica 78:1636-1638
  8. Chia-Li Wei, Shiou-Huei Chao, Wen-Bin Tsai, Pei-Shan Lee, Nai-Hung Tsau, Jhih-Shan Chen, Wen-Lin Lai, James Ching-Yueh Tu, and Ying-Chieh Tsai. (2013) Analysis of bacterial diversity during the fermentation of inyu, a high-temperature fermented soy sauce, using nested PCR-denaturing gradient gel electrophoresis and the plate count method. Food Microbiology 33(2):252-61.
  9. Sheng-Chia Chen, Chieh-Yi Shen, Te-Ming Yen, Hui-Chia Yu, Ting-Hao Chang, Wen-Lin Lai* and Shwu-Huey Liaw*. (2013) Evolution of vitamin B2 biosynthesis: eubacterial RibG and fungal Rib2 deaminases. Acta Cryst. D69, 227–236 (Co-corresponding author)
  10. Chih-Chieh Hsu, Wen-Lin Lai, Kuei-Chin Chuang, Meng-Hwan Lee, Ying-Chieh Tsai. (2013) The inhibitory activity of linalool against the filamentous growth and biofilm formation in Candida albicans. Medical mycology51(5):473-82. 
  11.  Yu-Ling Lin, Wen-Lin Lai, Horng-jyh Harn, Pei-Hsiu Hung, Ming-Chang Hsieh, Kai-Fu Chang, Xiao-Fan Huang, Kuang-Wen Liao, Ming-Shih Lee and Nu-Man Tsai*. (2013) The Methanol Extract of Angelica sinensis Induces Cell Apoptosis and Suppresses Tumor Growth in Human Malignant Brain Tumors. Evidence- Based Complementary and Alternative Medicine 2013:394636 (Equal first author)

     

 

 

期刊論文------研討會論文

 

 

  1. C. S, Hsu, W. L. Lai, and Y. C. Tsai. (2001) Expression, site-directed mutagenesis and characterization of Alcaligenes faeclais DA1 D-aminoacylase. Abstracts of the Sixteenth Joint Annual Conference of Biomedical Sciences. p. 110.
  2. Wen-Lin Lai and Ying-Chieh Tsai (2005) Structural and Functional Characterization of D-Aminoacylase from Alcaligenes faecalis DA1. International Symposium on Biocatalysis and Biotechnology for Functional Foods and Industrial Products (ISBB). National Chung-Hsing University, Taichung, Taiwan.
  3. Huang, C. H., Lai, W. L. Chen, C. C. Tsai, Y. C. and Liaw, S. H., (2006) Functional roles of the double covalent linkages of FAD in glucooligosaccharide oxidase from Acremonium strictum. The 11th symposium on recent advances in Biophysics.
  4. Yi-Tsz Liu, Meng-Hwan Lee, Ying-Chieh Tsai, Wen-Lin Lai. (2012) Fungicidal Activity of Citral against Malassezia furfur with Apoptotic Mechanism. The 27th joint annual conference of biomedical sciences.
  5. Yi-Yen Huang, Yin-Shen Lin, Jiunn-Horng Lin, Shiang-Jyi Hwang, Wen-Lin Lai, Meng-Hwan Lee. (2012) Immunoproteomic analysis of Bordetella bronchiseptica. 中華民國獸醫學會暨台灣省畜牧獸醫學會聯合年會
  6. Yi-Tsz Liu, Shih-Mei Chen, Chu-Yi Yao, Meng-Hwan Lee, Wen-Lin Lai. (2013) The Effect of Cymbopogon citrates Extract on Human Keratinocyte HaCat Cultured with Malassezia furfur. The 28th joint annual conference of biomedical sciences.
  7. Shih-Mei Chen, Yi-Tsz Liu, Shih-Yun Lin, Meng-Hwan Lee, Wen-Lin Lai. (2013) The Inhibitory Activity of Zanthoxylum armatum Extract Against the Filamentous Growth and Biofilm Formation by Candida albicans. The 28th joint annual conference of biomedical sciences
  8. M. H. Lee , W. L. Lai and Y. S. Lin. (2013) Characterization of bile salt hydrolase of Enterococcus hirae isolated from porcine milk. 第22屆中國畜牧學會第1次會員大會。

期刊論文------專書

 

Wen-Lin Lai and Ying-Chieh Tsai (2007) Structural and Functional Characterization of D-Aminoacylase from Alcaligenes faecalis DA1. Chapter 28 In Jei-Fu Shaw, Ching T. Hou (Ed.) Biocatalysis and Biotechnology for Functional Foods and Industrial Products; CRC Press, Florida, USA.